This study was carried out between October 2020 and October 2021 with the aim of determining sustainable management options and nutrition for the domestication of Mormyridae fish species living in the lower reaches of the Sanaga River in central Cameroon. For this purpose, 451 specimens collected from local fishermen were identified and grouped into 4 genera and 7 species (20.84% Campylomormyrus phantasticus (Pellegrin), 5.32% Hippopotamyrus castor Pappenheim, 24.61% Mormyrops anguilloides (Linnaeus), 18.63% Mormyrops caballus (Pellegrin), 4.66% Mormyrops zanclirostris (Günther, 1867), 15.52% Mormyrus rume Valenciennes, and 10.42% Mormyrus tapirus Pappenheim). Fishes were measured, and parameters were obtained after dissection using intestinal morphometric characteristics and stomach content analysis methods. The emptiness coefficient varied from 0% (Hippopotamyrus castor and Mormyrops zanclirostris) to 26.66% (Mormyrus rume). The relative mass of the intestine was low in all studied species; the intestinal coefficient and the Zihler index of all these species are within the range of carnivorous species. Analysis of stomach contents revealed a broad food spectrum containing twelve categories of prey. Insects, macrophytes and larval shelters were the preferred foods of Mormyrops anguilloides, Mormyrops caballus and Mormyrops zanclirostris, while insect larvae and larval shelters were the preferred prey for other species. Site and season had little effect on the categories of prey consumed by these species.